Week7: Improve gait results in THA patient by biomechanical device

THA,  total hip arthroplasty (Total hip replacement)  is a surgical procedure in which the hip joint is replaced by a prosthetic implant. The patient may not get used to their hip after the replacement. There are Foot-worn biomechanical device which is non-invasive can improve the gait result. It is worked by correcting the patient gait as they may walk clumsily after hip replacement.


Of 19 patients enrolled in the study – some of whom were admitted 3 months postoperatively – 50.3% showed significantly improved gait velocity, 22.9% had significantly improved step length and 16.9% had significantly improved single limb support, according to the abstract.

In order to help patient quickly recover from total hip replacement, physiotherapy are encourage to conduct. With the assistant of this biomechanical device, the patient can recover faster than normal.

Reference: Foot-worn biomechanical device improves gait results in THA patients: http://www.healio.com/orthopedics/hip/news/online/%7Be1038e9f-22f9-42e5-8abd-90c11b804ea9%7D/foot-worn-biomechanical-device-improves-gait-results-in-tha-patients

Picture: http://upload.wikimedia.org/wikipedia/commons/2/2f/Hip_replacement_Image_3684-PH.jpg




Week6: New way to monitor respiratory system accurately

When children have a body check on respiration, they may be discomfort by the medical instrument attach on their body. Doctors found that they may feel uncomfortable, so they got anxious. Therefore, the examination of respiratory system are not accurate as the respiration rate may affected.


Assisted by Dr Reza Saatchi, PhD Student Abdulkadir Hamidu Alkali took on the task of designing and developing the equipment as part of his PhD in Medical Electronics.

Abdulkadir developed a new, cutting edge ‘4fa’ respiration monitoring technique. 4fa works through recording thermal imagery of the patients as they breathe. It has the ability to identify areas of the face affected by respiration and from there it can monitor and record a patient’s respiration. The design also has the unique ability to identify and constantly track the patient’s face without being distracted by other heat signals in the background.

4fa works without wires and it is non-invasive, different from the traditional method. So this method can enhance the efficiency of the doctors as they can get a more accurate result. Moreover, children will not be stressed and feeling discomfort on this examination. Also, this technology can monitor the patient overnight, it can reduce the nurse workload. When the device detected any abnormal cases, the doctor can surely know what is going on, and save the patient life.


New ways to monitor children’s respiration: http://www.news-medical.net/news/20131118/New-ways-to-monitor-childrene28099s-respiration.aspx

Picture: http://my-internet-hospital.blogspot.hk/2010/10/respiratory-system-examination-methods.html

Week5: Retrograde Gene Therapy On Human Heart are new to the world

Ernie Lively is a actor in America, he had suffered severe heart attack in 2003. Luckily he survived from this accident, but unfortunately his heart was deteriorating after that. His heart became malfunctioning that the blood leaving his heart gradually decline.

Amit Patel, M.D., director of Clinical Regenerative Medicine and Tissue Engineering and an associate professor in the Division of Cardiothoracic Surgery at the University of Utah School of Medicine meet with Ernie Lively. Ernie Lively became his patient. Patel found that usual treatment were not working on Lively as his aorta and coronary arteries were dying. Thereby, Patel uses stem cell therapy.

“This month, Lively got his wish when he became the first patient in the world to undergo retrograde gene therapy at University of Utah Hospital, a novel procedure designed to deliver stem cells to the heart to repair damaged muscle and arteries in the most minimally invasive way possible.”

The unique gene therapy doesn’t involve viruses (a rarity for gene therapy, Patel notes) and is pure human DNA infused into patients. The DNA, called SDF-1, is a naturally occurring substance in the body that becomes a homing signal for a patient’s body to use its own stem cells to go to the site of an injury.

There are many people in the world suffering from heart diseases, stem cell therapy indeed can help them to tackle diseases. The first success treatment on Lively can obviously bring hope to all the patient. As it does not involve viral factors, it is regarded as safe therapy. Hope this treatment can be popular and heal more patient.



Historic First Procedure Performed Using Technique of Retrograde Gene Therapy On Human Heart:  http://www.sciencedaily.com/releases/2013/11/131127170105.htm

Picture: http://antiaging-products.net/stem-cell-therapy/

Week4: The most advanced microscope ever

Microscope can help human to have a closer look into an object. Especially for the objects that are too small for the naked eyes. The conventional microscopes are the optical one. The principle is magnifying image by lens. But nowadays, when scientists have to investigate objects down to nanometer and picometer, they cannot use optical microscopes. The electron microscope is used instead to avoid the diffract of light.

The most advanced microscope, Scanning Transmission Electron Holography Microscope. It is 7-tonne, 4.5-metre tall. The STEHM is a one-of-a-kind machine built for UVic in Japan by Hitachi High Technologies Canada and is the highest-resolution microscope in the world. It will allow researchers to see things 20 million times smaller than the tiniest thing the unaided human eye can see.

the STEHM uses an electron beam and holography techniques to observe the inside of materials and their surfaces to an expected resolution smaller than the size of an atom. Standard high-resolution microscopes have about 20 lenses for imaging the specimen, the STEHM has 50. The microscope is so sensitive that its image could be affected by little more than a passing cloud. For this reason, it is housed in a special self-contained, extra-tall room that is anchored to bedrock and encased in eight inches of insulation sandwiched between layers of galvanized steel.

This microscope is undoubtedly wonderful for scientists, medical researchers can use it to have better understand subatomic structures relevant to medical diagnostics.




Week3: 3-D printing are able to ”print” organs

3D printing is a process of making a three-dimensional solid object of virtually any shape from a digital model. 3D printing technology is used for both prototyping and distributed manufacturing with applications in architecture, construction (AEC), industrial design, automotive, aerospace, military, engineering, civil engineering, dental and medical industries, and more importantly, biotech.

For some patient who got organ failure, they have hope on 3D printing. It is because scientists have been printed kidney, and it could survive for 1 day. Further research is needed in order to implant the 3D printed human organs into patients.

In some sense 3D printing organs can resolve the ethics issue raised from implanting animal organs or organs cloning. Implanting animal organs have potential hazard that it may cause unpredictable diseases. Moreover, human who have been implanted animal organs may have a chance to be discriminated by others. On the other hand, 3D printing organs will not bring ethic issue that have just stated.

3D printing organ


3D printing: http://en.wikipedia.org/wiki/3D_printing

Picture: http://www.singularityweblog.com/3d-printing-is-bio-printing-the-future-of-organ-replacement/